United States Department of Veterans Affairs
Research Advisory Committee on Gulf War Veterans' Illnesses

Research Update - January 2006

 

The following journal articles were distributed for review in January 2006.  You can access the article's abstract by copying the paper title and pasting it into the search bar of the PubMed website, linked here. 

 

Research Relevant to Gulf War Service and Exposures
 
1. Gastroenteritis outbreak in British troops, Iraq .   (Bailey MS.  Emerg Infect Dis.  Oct 2005; 11(10): 1625-1628)
 
2. Long-term complications of sulphur mustard poisoning in severely intoxicated Iranian veterans.   (Balali-Mood M, et al.  Fundam Clin Pharmacol.  Dec 2005; 19(6): 713-721)
 
3. JP-8 jet fuel exposure and divided attention test performance in 1991 Gulf War veterans.   (Bell IR, et al.  Aviat Space Environ Med.  Dec 2005; 76(12): 1136-1144)
 
4. Serine hydrolase targets of organophosphorus toxicants.   (Casida JE, Quistad GB.  Chem Biol Interact.  Dec 15 2005; 158: 277-283.  Epub Oct 21, 2005.)
 
5. Current issues in organophosphate toxicology.   (Costa LG.  Clin Chim Acta.  Dec 5, 2005; [Epub ahead of print])
 
6. Molecular analysis of hprt mutations generated in Chinese hamster ovary EM9 cells by uranyl acetate, by hydrogen peroxide, and spontaneously.   (Coryell VH, Stearns DM.  Mol Carcinog.  Jan 2006; 45(1): 60-72)
 
7. Gene expression profiles of the rat brain both immediately and 3 months following acute sarin exposure.   (Damodaran TV, et al.  Biochem Pharmacol.  Dec 22, 2005; [Epub ahead of print])
 
8. Gulf War illness.   (Deahl M.  Br J Hosp Med (Lond).  Nov 2005; 66(11): 608-609)
 
9. Mental health comorbidity patterns and impact on quality of life among veterans serving during the first Gulf War.   (Forman-Hoffman VL, et al.  Qual Life Res.  Dec 2005; 14(10): 2303-2314)
 
10. Understanding the effect of deployment on the risk of fatal motor vehicle crashes: A nested case-control study of fatalities in Gulf War era veterans. 1991-1995.    (Hooper TI, et al.  Accid Anal Prev.  Jan 4, 2006; [Epub ahead of print])
 
11. Resolving disputes about toxicological risks during military conflict: The U.S. Gulf War Experience.   (Hyams KC, et al.  Toxicol Rev.  2005; 24(3): 167-180)
 
12. Evaluation of epidemiologic and animal data associating pesticides with Parkinson’s disease.   (Li AA, et al.  J Occup Environ Med.  Oct 2005; 47(10): 1059-1087)
 
13. Characterizing Gulf War illnesses: Neurally mediated hypertension and postural tachycardia syndrome.    (Lucas KE, et al.  Am J Med.  Dec 2005; 118(12): 1421-1427)
 
14. Determination of 238U/235U, 236U/238U and uranium concentration in urine using SF-ICP-MS and MC-ICP-MS: An interlaboratory comparison.   (Parrish RR, et al.  Health Phys.  Feb 2006; 90(2): 127-138)
 
15. A reassessment of the neurotoxicity of pyrethroid insecticides.   (Ray DE, Fry JR.  Pharmacol Ther.  Nov 28, 2005; [Epub ahead of print])
 
16. Hydrolytic metabolism of pyrethroids by human and other mammalian carboxylesterases.   (Ross MK, et al.  Biochem Pharmacol.  Dec 29, 2005; [Epub ahead of print])
 
17. Posttraumatic Stress Disorder and Health Status: The Veterans Health Study.   (Spiro A 3rd, et al.  J Ambul Care Manage.  Jan-Mar 2006; 29(1): 71-86)
 
18. In vitro immune toxicity of depleted uranium: Effects on murine macrophages, CD4+ T cells, and gene expression profiles.   (Wan B, et al.  Environ Health Perspect.  Jan 2006; 114(1): 85-91)
 
19. Monitoring cholinesterases to detect pesticide exposure.   (Wilson BW, et al.  Chem Biol Interact.  Dec 15, 2005; 157-158: 253-256)
 
Research on Evaluation/Treatment of Chronic Multisymptom Illnesses
 
1. A chronic fatigue syndrome – related proteome in human cerebrospinal fluid.   (Baraniuk JN, et al.  BMC Neurol.  Dec 1 2005; 5(1): 22 [Epub ahead of print])
 
2. Cognitive dysfunction relates to subjective report of mental fatigue in patients with chronic fatigue syndrome.   (Capuron L, et al.  Neuropsyhcopharmacology.  Jan 4, 2006; [Epub ahead of print])
 
3. Behavioral insomnia therapy for fibromyalgia patients: a randomized clinical trial.   (Edinger JD, et al.  Arch Intern Med.  Nov 28, 2005; 165(21): 2527-2535)
 
4. Efficacy of milnacipran in patients with fibromyalgia.   (Gendreau RM, et al.  J Rheumatol.  Oct 2005; 32(10): 1975-1985)
 
5. Psychological stress and fibromyalgia: A review of the evidence suggesting a neuroendocrine link.   (Gupta A, Silman AJ.  Arthritis Rev.  2004; 6(3): 98-106. Epub Apr 7, 2004)
 
6. Orthostatic instability in a population-based study of chronic fatigue syndrome.   (Jones JF, et al.  Am J Med.  Dec 2005; 118(12): 1415)
 
7. Oxidative stress levels are raised in chronic fatigue syndrome and are associated with clinical symptoms.   (Kennedy G, et al.  Free Radic Biol Med.  Sep 1, 2005; 39(5): 584-589)   
 
8. Lower serum zinc in Chronic Fatigue Syndrome (CFS): Relationships to immune dysfunctions and relevance for the oxidative stress status in CFS.   (Maes M, et al.  J Affect Disord.  Dec 7, 2005; [Epub ahead of print])
 
9. In chronic fatigue syndrome, the decreased levels of omega-3 poly-unsaturated fatty acids are related to lowered serum zinc and defects in T cell activation.   (Maes M, et al.  Neuro Endocrinol Lett.  Dec 28, 2005; 26(6) [Epub ahead of print])
 
10. Chronic fatigue syndrome is associated with diminished intracellular perforin.   (Maher KJ, et al.  Clin Exp Immunol.  Dec 2005; 142(3): 505-511)
 
11. Increase of free Mg2+ in the skeletal muscle of chronic fatigue syndrome patients.   (McCully KK, et al.  Dyn Med.  Jan 11 2006; 5(1): 1 [Epub ahead of print])
 
12. Microcirculation abnormalities in patients with fibromyalgia – measured by capillary microscopy and laser fluxmetry.   (Morf S, et al.  Arthritis Res Ther.  2005; 7(2): R209-R216)
 
13. Impairments of the 2-5A synthetase/RNase L pathway in chronic fatigue syndrome.   (Nijs J, De Meirleir K.  In Vivo.  Nov-Dec 2005; 19(6): 1013-1021)
 
14. The vanilloid receptor as a putative target of diverse chemicals in multiple chemical sensitivity.   (Pall ML, Anderson JH.  Arch Environ Health.  Jul 2004; 59(7): 363-375)
 
15. Chronic fatigue syndrome – a clinically empirical approach to its definition and study.   (Reeves WC, et al.  BMC Med.  Dec 15, 2005; 3(1): 19 [Epub ahead of print])
 

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