United States Department of Veterans Affairs
Research Advisory Committee on Gulf War Veterans' Illnesses

Research Update - May 2005

 The following journal articles were distributed for review in May 2005.  You can access the article's abstract by copying the paper title and pasting it into the search bar of the PubMed website, linked here. 

Research Relevant to Gulf War Service and Exposures
 
1. Epidemiology of multiple sclerosis in Kuwait: New trends in incidence and prevalence.  (Alshubaili AF, et al.  Eur Neurol.  Apr 28, 2005; 53(3): 125-131)
 
2. Chemical sensitivity in symptomatic Cambodia veterans.  (Bischoff EW, et al.  Arch Environ Health.  Dec 2003; 58(12): 740-745)
 
3. Neurodegenerative memory disorders: a potential role of environmental toxins.  (Caban-Holt A, et al.  Neurol Clin.  May 2005; 23(2): 485-521)
 
4. ALS-Vet linkage pursued.  (Couzin J.  Science.  May 13, 2005; 308(5724): 937)
 
5. Chronic and delayed-onset mustard gas keratitis: report of 48 patients and review of literature.  (Javadi MA, et al.  Ophthalmology.  Apr 11, 2005; 112(4): 617-625)
 
6. Neuropathological studies of rats following multiple exposure to tri-ortho-tolyl phosphate, chlorpyrifos and stress.  (Jortner BS, et al.  Toxicol Pathol.  2005; 33(3): 378-385)
 
7. Neurologic symptoms in licensed private pesticide applicators in the agricultural health study.  (Kamel F, et al.  Environ Health Perspect .  April 15, 2005 [Epub ahead of print])
 
8. Effects of pesticides on the peripheral and central nervous system in tobacco farmers in Malaysia: studies on peripheral nerve conduction, brain-evoked potentials and computerized posturography.  (Kimura K, et al.  Ind  Health.  Apr 2005; 43(2): 285-294)
 
9. Leishmaniasis among soldiers of stabilization forces in Iraq. Review article.(Korzeniewski K, Olszanski R.  Int Marit Health.  2004; 55(1-4): 155-163)
 
10. Genetic and other sources of variation in the activity of serum paraoxonase/diazoxonase in humans: consequences for risk from exposure to diazinon.  (O’Leary KA, et al.  Pharmacogenet Genomics.  Jan 2005; 15(1): 51-60)
 
11. Effect of depleted uranium weapons used in the Balkan war on the incidence of cervical intraepithelial neoplasia (CIN) and invasive cancer of the cervix in Greece.  (Papathanasiou K, et al.  Clin Exp Obstet Gynecol.  2005; 32(1): 58-60)
 
12. Acetylcholinesterase inhibitors reduce brain and blood interleukin-1beta production.  (Pollak Y, et al.  Ann Neurol.  May 2005; 57(5): 741-745)
 
13. Blood acylpeptide hydrolase activity is a sensitive marker for exposure to some organophosphate toxicants.  (Quistad GB, et al.  Toxicol Sci.  May 11, 2005 [Epub ahead of print])
 
14. Are vasoactive neuropeptide autoimmune fatigue-reduced disorders mediated via G protein-couple receptors?  (Staines D.  Med Hypotheses.  2005; 65(1): 29-31)
 
15. Butyrylcholinesterase: impact on symptoms and progression of cognitive impairment.  (Tasker A, et al.  Expert Rev Neurother.  Jan 2005; 5(1): 101-106)
 
16. Vaccination alone or in combination with pyridostigmine promotes and prolongs activation of stress-activated kinases induced by stress in the mouse brain.  (Wang D, et al.  J Neurochem.  May 2005; 93(4): 1010-1020)
 
Research on Evaluation/Treatment of Chronic Multisymptom Illnesses
 
1. Prospective observational study of treatments for unexplained chronic fatigue.  (Bentler SE, et al.  J Clin Psychiatry.  May 2005; 66(5): 625-632)
 
2. Pregabalin for the treatment of fibromyalgia syndrome: results of a randomized, double-blind, placebo-controlled trial.  (Crofford LJ, et al.  Arthritis Rheum.  Apr 2005; 52(4): 1264-1273)
 
3. Predictors of outcome following treatment for chronic fatigue.  (Darbishire L, et al.  Br J Psychiatry.  Apr 2005; 186: 350-351)
 
4. Objective evidence of cognitive complaints in chronic fatigue syndrome: a BOLD fMRI study of verbal working memory.  (Lange G, et al.  Neuroimage.  Jun 1, 2005; 26(2): 513-524)
 
5. Current trends in neuropathic pain treatments with special reference to fibromyalgia.  (Offenbaecher M, Ackenheil M.  CNS Spectr.  Apr 2005; 10(4): 285-297)
 
6. A feasibility study comparing two treatment approaches for chronic fatigue syndrome in adolescents.   (Wright B, et al.  Arch Dis Child.  Apr 2005; 90(4): 369-372)
 

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