Research Advisory Committee on Gulf War Veterans' Illnesses
Research Update - October 2005
The following journal articles were distributed for review in October 2005. You can access the article's abstract by copying the paper title and pasting it into the search bar of the PubMed website, linked here.
Research Relevant to Gulf War Service and Exposures
1. Acute and long lasting cardiac changes following a single whole body exposure to sarin vapor in rats. (Allon N, et al. Toxicol Sci. Jul 20, 2005; [Epub ahead of print])
2. ALS and military service. (Ascherio A, et al. Neurology. Sep 27, 2005; 65(6): 972; author reply 972)
3. Complex view on poisoning with nerve agents and organophosphates. (Bajgar J. Act Medica (Hradec Kralove ). 2005; 48(1): 3-21)
4. Autonomic impairment in amyotrophic lateral sclerosis. (Baltadzhieva R, et al. Curr Opin Neurol. Oct 2005; 18(5): 487-493)
5. Changes of acetylcholinesterase activity after long-term exposure to sarin vapors in rats. (Bartosova-Sevelova L, Bajgar J. Hum Exp Toxicol. Jul 2005; 24(7): 363-367)
6. Incarceration and veterans of the first Gulf War. (Black DW, et al. Mil Med. Jul 2005; 170(7): 612-618)
7. Evaluation of anthrax vaccination in Denmark. (Bork KH, et al. Ugeskr Laeger. Sep 5, 2005; 167(36): 3390-3393) [Note: Non-English language publication]
8. Gene bank proposal draws support – and a competitor. (Couzin J. Science. Jul 29, 2005; 309; 684-685)
9. Nature of stress: Differential effects on brain acetylcholinesterase activity and memory in rats. (Das A, et al. Life Sci. Sep 16, 2005; 77(18): 2299-2311)
10. Role of paraoxonase (PON1) status in pesticide sensitivity: genetic and temporal determinants. (Furlong CE, et al. Neurotoxicology. Aug 2005; 26(4): 651-659)
11. Gulf War Syndrome – the story so far. (Greenberg N, Wessely S. J R Nav Med Serv. 2005; 91(1): 4-11)
12. Teratogenicity of depleted uranium aerosols: A review from an epidemiological perspective. (Hindin R, et al. Environ Health. Aug 26, 2005; 4(1): 17 [Epub ahead of print])
13. Operation Iraqi Freedom: the Landstuhl Regional Medical Center experience. (Johnson BA, et al. J Foot Ankle Surg. May-Jun 2005; 44(3): 177-183)
14. Measurement of the 234U/238U ratio by MC-ICPMS in drinking water, hair, nails, and urine as an indicator of uranium exposure source. (Karpas Z, et al. Health Phys. Oct 2005; 89(4): 315-321)
15. Insomnia as a sequela of sarin toxicity several years after exposure in Tokyo subway trains. (Kawada T, et al. Percept Mot Skills. Jun 2005; 100(3 Pt 2): 1121-1126)
16. Evaluation of chronic gastrointestinal symptoms following Persian Gulf War exposure. (Koch TR, Emory TS. Mil Med. Aug 2005; 170(8): 696-700)
17. Micronuclei frequencies in peripheral blood lymphocytes of individuals exposed to depleted uranium. (Krunic A, et al. Arh Hig Rada Toksikol. Sep 2005; 56(3): 227-232)
18. Effects of sarin on the operant behavior of guinea pigs. (Langston JL, et al. Neurotoxicol Teratol. Jul 18, 2005; [Epub ahead of print])
19. Biological monitoring and surveillance results of Gulf War I veterans exposed to depleted uranium. (McDiarmid MA, et al. Int Arch Occup Environ Health. Aug 2, 2005; 1-11 [Epub ahead of print])
20. Bioaccumulation and behavioral effects of depleted uranium in rats exposed to repeated inhalations. (Monleau M, et al. Neurosci Lett. Aug 19, 2005; [Epub ahead of print])
21. Effects per se of organic solvents in the cerebral acetylcholinesterase of rats. (Obregon AD, et al. Neurochem Res. Mar 2005; 30(3): 379-384)
22. Low-level exposure to organophosphate pesticides leads to restrictive lung dysfunction. (Peiris-John RJ, et al. Respir Med. Oct 2005; 99(1): 1319-1324)
23. Pesticide metabolism in humans, including polymorphisms. (Rose RL, et al. Scand J Work Environ Health. 2005; 31 Suppl 1: 156-163; discussion 119-122)
24. The long term safety of anthrax vaccine, pyridostigmine bromide (PB) tablets, and other risk factors among reserve component veterans of the first Persian Gulf War. (Schumm WR, et al. Med Veritas. 2005; 2: 348-362)
25. Prediction of renal concentrations of depleted uranium and radiation dose in Gulf War veterans with embedded shrapnel. (Squibb KS , et al. Health Phys. Sep 2205; 89(3): 267-273)
26. Uranyl acetate induces hprt mutations and uranium-DNA adducts in Chinese hamster ovary EM9 cells. (Stearns DM, et al. Mutagenesis. Sep 29, 2005; [Epub ahead of print])
27. Adverse reactions to anthrax immunization in Danish military personnel deployed to Iraq. (Svane C, et al. Ugeskr Laeger. Sep 5, 2005; 167(36): 3393-3396 [Note: Non-English language publication]
28. Diagnostic aspects of organophosphate poisoning. (Worek F, et al. Toxicology. Jul 25, 2005; [Epub ahead of print])
29. Infectious disease during wartime. (Zapor MJ, Moran KA. Curr Opin Infect Dis. Oct 2005; 18(5): 395-399)
Research on Diagnosis/Treatment of Chronic Multisymptom Illnesses
1. Pharmacologic treatment of fibromyalgia. (Baker K, Barkhuizen A. Curr Pain Headache Rep. Oct 2005; 9(5): 301-306)
2. Exercise and cognitive performance in chronic fatigue syndrome. (Cook DB, et al. Med Sci Sports Exerc. Sep 2005; 37(9): 1460-1467)
3. A randomized clinical trial of individualized home-based exercise programme for women with fibromyalgia. (Da Costa D, et al. Rheumatology (Oxford ). Jul 19, 2005; [Epub ahead of print])
4. A randomized controlled trial of dehydroepiandrosterone in postmenopausal women with fibromyalgia. (Finckh A, et al. J Rheumatol. Jul 2005; 32(7): 1336-1340)
5. Abnormalities of cardiovascular neural control and reduced orthostatic tolerance in patients with primary fibromyalgia. (Furlan R, et al. J Rheumatol. Sep 2005; 32(9): 1787-1793)
6. Treatment of fibromyalgia with formula acupuncture: investigation of needle placement, needle stimulation, and treatment frequency. (Harris RE, et al. J Altern Complement Med. Aug 2005; 11(4): 663-671)
7. A randomized, double-blind, placebo-controlled trial of pramipexole, a dopamine agonist, in patients with fibromyalgia receiving concomitant medications. (Holman AJ, Myers RR. Arthritis Rheum. Aug 2005; 52(8): 2495-2505)
8. Gene expression in peripheral blood mononuclear cells from patients with chronic fatigue syndrome. (Kaushik N, et al. J Clin Pathol. Aug 2005; 58(8): 826-832)
9. Oxidative stress levels are raised in chronic fatigue syndrome and are associated with clinical symptoms.(Kennedy G, et al. Free Radic Biol Med. Sep 1, 2005; 39(5): 584-589)
10. Evaluation of reboxetine, a noradrenergic antidepressant, for the treatment of fibromyalgia and chronic low back pain. (Krell HV, et al. Psychosomatics. Sep-Oct 2005; 46(5): 379-384)
11. Association of chronic fatigue syndrome with human leucocyte antigen class II alleles. (Smith J, et al. J Clin Pathol. Aug 2005; 58(8) 860-863)
