Citation Nr: 0820379 Decision Date: 06/20/08 Archive Date: 06/25/08 DOCKET NO. 99-22 327A ) DATE ) ) On appeal from the Department of Veterans Affairs Regional Office in Newark, New Jersey THE ISSUES 1. Entitlement to service connection for residuals of infectious mononucleosis. 2. Entitlement to service connection for chronic liver disease. REPRESENTATION Appellant represented by: Vietnam Veterans of America WITNESS AT HEARING ON APPEAL Appellant and E.N. ATTORNEY FOR THE BOARD J. Barone, Counsel INTRODUCTION The appellant had active service from September 1968 to September 1971. This case comes before the Board of Veterans' Appeals (the Board) on appeal from a July 1997 rating decision of the Newark, New Jersey, VA Regional Office (RO). This case has previously come before the Board. In October 2003, the Board remanded the matters to the agency of original jurisdiction (AOJ) for additional development. The appellant was afforded a travel Board hearing before the undersigned Veterans Law Judge in September 2002. A transcript of the hearing has been associated with the claims file. In December 2005, the Board reopened the claim of entitlement to service connection for residuals of mononucleosis and denied the claim on the merits. It also denied entitlement to service connection for chronic liver disease. The veteran appealed to the Court of Appeals for Veterans Claims (Court). In a February 2008 memorandum decision, the Court vacated the Board's December 2005 decision and remanded the appeal for further proceedings. FINDINGS OF FACT 1. No residuals of infectious mononucleosis are shown. 2. The evidence shows that the appellant did not have liver disease during active service or within one year of separation; and that his cryptogenic cirrhosis is not otherwise related to active service, including as a residual of infectious mononucleosis or exposure to Agent Orange. CONCLUSIONS OF LAW 1. Infectious mononucleosis residuals were not incurred in or aggravated by service. 38 U.S.C.A. § 1110 (West 2002); 38 C.F.R. § 3.303 (2007). 2. A liver disability, disorder, diagnosed as cryptogenic cirrhosis, was not incurred in or aggravated by service and may not be presumed to have been incurred therein. 38 U.S.C.A. §§ 1101, 1110, 1112, 1113 (West 2002); 38 C.F.R. § 3.303, 3.307, 3.309 (2007). REASONS AND BASES FOR FINDINGS AND CONCLUSIONS The Veterans Claims Assistance Act of 2000 (VCAA) describes VA's duty to notify and assist claimants in substantiating a claim for VA benefits. 38 U.S.C.A. §§ 5100, 5102, 5103, 5103A, 5107, 5126 (West 2002 & Supp. 2007); 38 C.F.R. §§ 3.102, 3.156(a), 3.159 and 3.326(a) (2007). Upon receipt of a complete or substantially complete application for benefits, VA is required to notify the claimant and his representative of any information, and any medical or lay evidence, that is necessary to substantiate the claim. 38 U.S.C.A. § 5103(a) (West 2002 & Supp. 2007); 38 C.F.R. § 3.159(b) (2007); Quartuccio v. Principi, 16 Vet. App. 183 (2002). Proper VCAA notice must inform the claimant of any information and evidence not of record (1) that is necessary to substantiate the claim; (2) that VA will seek to provide; and (3) that the claimant is expected to provide; and (4) must ask the claimant to provide any evidence in his possession that pertains to the claim, in accordance with 38 C.F.R. § 3.159(b)(1). VCAA notice should be provided to a claimant before the initial unfavorable RO decision on a claim. See Pelegrini v. Principi, 18 Vet. App. 112 (2004); Mayfield v. Nicholson, 19 Vet. App. 103 (2005), rev'd on other grounds, 444 F.3d 1328 (Fed. Cir. 2006). During the pendency of this appeal, on March 3, 2006, the Court issued a decision in the consolidated appeal of Dingess/Hartman v. Nicholson, 19 Vet. App. 473 (2006), which held that the VCAA notice requirements of 38 U.S.C.A. § 5103(a) and 38 C.F.R. § 3.159(b) apply to all five elements of a service connection claim. Those five elements include: 1) veteran status; 2) existence of a disability; 3) a connection between the veteran's service and the disability; 4) degree of disability; and 5) effective date of the disability. The Court held that upon receipt of an application for a service-connection claim, 38 U.S.C.A. § 5103(a) and 38 C.F.R. § 3.159(b) require VA to review the information and the evidence presented with the claim and to provide the claimant with notice of what information and evidence not previously provided, if any, will assist in substantiating or is necessary to substantiate the elements of the claim as reasonably contemplated by the application. Id. at 486. In the present case, the veteran's claim was received prior to the enactment of the VCAA. A letter dated in April 2001 explained the VCAA. The veteran was asked to advise VA if there were outstanding medical records showing that the claimed disabilities were related to service. He was told that the evidence should show that the claimed condition existed and there was a nexus to service, or that it was related to a condition for which service connection had already been established. He was also advised that he could submit evidence of continuity and tonicity of the claimed condition. The letter described how VA would assist the veteran in obtaining evidence. He was told that VA had requested records from the Social Security Administration (SSA). A March 2006 letter advised the veteran of the manner in which VA determines disability ratings and effective dates. The Board finds that any defect with respect to the timing of the VCAA notice requirement was harmless error. The content of the notice provided to the veteran fully complied with the requirements of 38 U.S.C.A. § 5103(a) and 38 C.F.R. § 3.159(b) regarding VA's duty to notify. The veteran has been provided with every opportunity to submit evidence and argument in support of the claim and to respond to VA notices. Although the veteran received inadequate preadjudicatory notice, and that error is presumed prejudicial, the record reflects that he was provided with a meaningful opportunity such that the preadjudicatory notice error did not affect the essential fairness of the adjudication now on appeal. The Board finds that the purpose behind the notice requirement has been satisfied because the veteran has been afforded a meaningful opportunity to participate effectively in the processing of his claims. As the Federal Circuit Court has stated, it is not required "that VCAA notification must always be contained in a single communication from the VA." Mayfield, supra, 444 F.3d at 1333. With respect to VA's duty to assist, identified treatment records have been obtained and associated with the record. VA examinations have been conducted, and opinions requested. Records have been obtained from SSA. The veteran was afforded the opportunity to testify before the undersigned. The veteran has not identified any additional evidence or information which could be obtained to substantiate the claim. The Board is also unaware of any such outstanding evidence or information. Therefore, the Board is also satisfied that the RO has complied with the duty to assist requirements of the VCAA and the implementing regulations. For the foregoing reasons, it is not prejudicial to the veteran for the Board to proceed to a final decision in this appeal. Analysis Initially, the Board notes there has been no assertion of combat. Therefore, the provisions of 38 U.S.C.A. § 1154(b) (West 2002) are not for application. Service connection may be granted for disability resulting from personal injury suffered or disease contracted in the line of duty, or for aggravation of a preexisting injury suffered or disease contracted in the line of duty, in the active military, naval, or air service. 38 U.S.C.A. §§ 1110, 1131; 38 C.F.R. § 3.303(a). Service connection may also be granted for any disease initially diagnosed after discharge, when all the evidence, including that pertinent to service, establishes that the disease was incurred in service. 38 C.F.R. § 3.303(d). Direct service connection may not be granted without evidence of a current disability, evidence of in-service incurrence or aggravation of a disease or injury, and evidence of a nexus between the claimed in-service disease or injury and the present disease or injury. See Caluza v. Brown, 7 Vet. App. 498, 506 (1995) aff'd, 78 F.3d 604 (Fed. Cir. 1996) (table)]. For the showing of chronic disease in service, there is required a combination of manifestations sufficient to identify the disease entity, and sufficient observation to establish chronicity at the time. 38 C.F.R. § 3.303(b). If chronicity in service is not established, a showing of continuity of symptoms after discharge is required to support the claim. Service connection may also be granted for any disease diagnosed after discharge when all of the evidence establishes that the disease was incurred in service. 38 C.F.R. § 3.303(d). A chronic, tropical, or prisoner-of-war related disease, or a disease associated with exposure to certain herbicide agents, listed in 38 C.F.R. § 3.309 will be considered to have been incurred in service under the circumstances outlined in this section even though there is no evidence of such disease during the period of service. No condition other than the ones listed in 38 C.F.R. § 3.309(a) will be considered chronic. 38 U.S.C.A. §§ 1101, 1112, 1113, 1116; 38 C.F.R. § 3.307(a). A veteran who, during active military, naval, or air service, served in the Republic of Vietnam during the period beginning on January 9, 1962, and ending on May 7, 1975 shall be presumed to have been exposed during such service to an herbicide agent, unless there is affirmative evidence to establish that the veteran was not exposed to any such agent during that service. The last date on which such a veteran shall be presumed to have been exposed to an herbicide agent shall be the last date on which he or she served in the Republic of Vietnam during the period beginning on January 9, 1962, and ending on May 7, 1975. "Service in the Republic of Vietnam" includes service in the waters offshore and service in other locations if the conditions of service involved duty or visitation in the Republic of Vietnam. 38 U.S.C.A. § 1116(f); 38 C.F.R. § 3.307(a)(6)(iii). If a veteran was exposed to an herbicide agent during active military, naval, or air service, the following diseases shall be service-connected if the requirements of 38 U.S.C.A. § 1116, 38 C.F.R. § 3.307(a)(6)(iii) are met, even though there is no record of such disease during service, provided further that the rebuttable presumption provisions of 38 U.S.C.A. § 1113; 38 C.F.R. § 3.307(d) are also satisfied: chloracne or other acneform diseases consistent with chloracne, Hodgkin's disease, multiple myeloma, non-Hodgkin's lymphoma, acute and subacute peripheral neuropathy, porphyria cutanea tarda, prostate cancer, respiratory cancers (cancer of the lung, bronchus, larynx, or trachea), soft-tissue sarcomas (other than osteosarcoma, chondrosarcoma, Kaposi's sarcoma, or mesothelioma), diabetes mellitus, and chronic lymphocytic leukemia. 38 C.F.R. § 3.309(e). The diseases listed at 38 C.F.R. § 3.309(e) shall have become manifest to a degree of 10 percent or more at any time after service, except that chloracne or other acneform disease consistent with chloracne, porphyria cutanea tarda, and acute and subacute peripheral neuropathy shall have become manifest to a degree of 10 percent or more within a year, and respiratory cancers within 30 years, after the last date on which the veteran was exposed to an herbicide agent during active military, naval, or air service. 38 C.F.R. § 3.307(a)(6)(ii). Service connection on a presumptive basis for exposure to herbicides in Vietnam is limited to the following diagnoses: non-Hodgkin's lymphoma, soft-tissue sarcoma, chloracne or other acneform disease consistent with chloracne, Hodgkin's disease, porphyria cutanea tarda, respiratory cancers (cancer of the lung, bronchus, larynx, or trachea), multiple myeloma, Type 2 diabetes, acute and subacute peripheral neuropathy, and prostate cancer. See 38 U.S.C.A. § 1116(a)(2) (West 2002); 38 C.F.R. § 3.309(e) (2005). Further, VA regulation provides that with chronic disease shown as such in service (or within the presumptive period under 38 C.F.R. § 3.307) so as to permit a finding of service connection, subsequent manifestations of the same chronic disease at any later date, however remote, are service connected, unless clearly attributable to intercurrent causes. For the showing of chronic disease in service there is required a combination of manifestations sufficient to identify the disease entity, and sufficient observation to establish chronicity at the time, as distinguished from merely isolated findings or a diagnosis including the word "chronic." When the disease identity is established (leprosy, tuberculosis, multiple sclerosis, etc.), there is no requirement of evidentiary showing of continuity. Continuity of symptomatology is required only where the condition noted during service (or in the presumptive period) is not, in fact, shown to be chronic or where the diagnosis of chronicity may be legitimately questioned. When the fact of chronicity in service is not adequately supported, then a showing of continuity after discharge is required to support the claim. 38 C.F.R. 3.303(b). Service connection may be granted for any disease diagnosed after service when all the evidence establishes that the disease was incurred in service. 38 C.F.R. § 3.303(d); Combee v. Brown, 34 F.3d 1039, 1042 (Fed. Cir. 1994). When there is an approximate balance of positive and negative evidence regarding the merits of an issue material to the determination of the matter, the benefit of the doubt in resolving each such issue shall be given to the claimant. 38 U.S.C.A. § 5107(b) (West 2002). Initially, the Board notes that we have not adopted a treating physician rule nor has the Board determined that a diagnosis must be made during service. Rather, all evidence is considered. Familiarity with a patient is evidence to be considered. Similarly, consistency of the evidence is a fact to be considered when balancing the evidence. As noted by the Court, the probative value of medical evidence is based on the medical expert's personal observation of the patient, the physician's knowledge and skill in analyzing the data, and the medical conclusion that the physician reaches. Guerrieri v. Brown, 4 Vet. App. 467, 471 (1993). Essentially, the appellant asserts that his liver disease is related to service. More specifically, he contends that his cryptogenic cirrhosis is a result of in-service mononucleosis, exposure to Agent Orange during service in Vietnam, or some other disease in service, to include liver disease. The determination of this matter requires competent evidence. The appellant is competent to report his symptoms. His opinion in regard to etiology, however, is not competent evidence, as he is a layperson. Espiritu v. Derwinski, 2 Vet. App. 492, 495 (1992). On VA general medical examination in November 1971, the examiner noted a history of infectious mononucleosis with liver involvement, but indicated that such was not found on examination. Private medical records indicate that the veteran was diagnosed with end-stage liver disease of unknown etiology in October 1996. He had an extensive workup for etiology, which was nondiagnostic. A VA general medical examination was carried out in March 1997. The veteran's history was reviewed. The veteran reported that he was awaiting a liver transplant. He also denied history of nausea, vomiting, or diarrhea, as well as fevers or chills. The diagnosis was end-stage liver disease, etiology unknown. The veteran underwent a liver transplant in June 1997. An April 1998 statement from D.W.C., M.D. indicates that the veteran had been under his care since December 1992. He expressed his belief that the veteran's liver disease stemmed from earlier problems, first diagnosed in 1969. He noted that the veteran's exposure to Agent Orange in Vietnam may have played a role in the development of liver disease. He stated that there may be a direct association between the veteran's previous treatment for a liver disorder and infectious mononucleosis. Dr. C. reiterated that there may be a direct relationship between the veteran's previous liver disease and development of cryptogenic cirrhosis. A March 1999 opinion by two VA physicians, one of whom was a gastroenterologist, indicates that it was very unlikely that the veteran's infectious mononucleosis of 1969 was the cause of his cirrhosis diagnosed in 1996. An additional opinion was rendered by a VA physician in March 2003. The author indicated that he had completely reviewed the veteran's record and discussed the matter with a gastroenterologist. He concluded that it was not likely that the veteran's current problems with liver disease had any relationship to his bout with infectious mononucleosis in service. He noted that there was documentation of mononucleosis, but that according to the literature he had reviewed, severe or permanent hepatic dysfunction is exceedingly rare as a sequelae of infectious mononucleosis. He indicated that while almost 90 percent of patients with mononucleosis experience mild elevation of hepatic transaminases, mononucleosis was not an etiology for cirrhosis of the liver. He concluded that the veteran's liver disease did not have its onset in service. He pointed out that current medical records stated that the veteran was diagnosed with cryptogenic cirrhosis, meaning that no etiology for the liver disease was found. He also concluded that it was not likely that the veteran's liver disease was due to Agent Orange exposure, as there had been no scientific data to show any link between liver disease and such exposure. He again noted that the current records clearly indicated that the etiology of the veteran's cirrhosis was unknown and that there was no scientific basis to attribute the liver condition to either infectious mononucleosis or exposure to Agent Orange. A September 2002 letter from Dr. C. indicates his belief that the veteran's cirrhosis related to exposure to Agent Orange in service. A September 2005 document from C.N.B., M.D., is styled as an independent medical evaluation. Dr. B. indicated that he had reviewed the veteran's claims file and medical records, including service medical records, post-service medical records, imaging and laboratory reports, other medical opinions, and medical literature. He opined that the veteran's failed liver state was a result of "either/both an extension of some occult liver pathologic process that he had in service which raised his SGOT values or/and a result of this patients loss of hepatic reserve (hepatocytes) during service when he had months of elevated SGOT values." He maintained that the veteran had several months of elevated SGOT, from March 1969 to September 1969. He stated that his review of the military records did not indicate a return to normal levels. He opined that the liver pathology in service was the precursor to his liver failure in 1997. In support of his conclusion, he stated that the veteran developed a serious liver disease in service and had months of elevated liver enzymes consistent with an occult type of hepatitis. He indicated that the veteran was likely exposed to some sort of hepatic cell damaging infection or toxin in service, and that hepatitis was known to cause cirrhosis. He also noted that it took years to decades to develop end-stage liver disease in some occult hepatic processes. With respect to the VA medical opinion, Dr. B. it was known that hepatitis and mononucleosis cause end-stage liver disease by way of cirrhosis, and that the examiner did not discuss how the loss of reserve liver function could cause the veteran's liver to fail prematurely. He also indicated that the examiner did not provide any literature to support his opinion. Having again carefully reviewed the evidence pertaining to this appeal, the Board has determined that service connection is not warranted. In this regard the Board notes that the March 2003 VA examiner specifically stated that liver disease did not have an onset in service. In reaching his opinion, he conducted a complete review of the veteran's record and consulted a gastroenterologist. He also cited to appropriate literature in support of his conclusion, noting that severe or permanent hepatic dysfunction is exceedingly rare as a sequelae of infectious mononucleosis, and that while almost 90 percent of patients with mononucleosis experience mild elevation of hepatic transaminases, mononucleosis was not an etiology for cirrhosis of the liver. To the extent that Dr. B. opined that the laboratory testing during service indicated that the appellant had liver disease, service medical records are negative for a diagnosis of liver disease and at separation in September 1971 the genito urinary system and abdomen and viscera were normal. Moreover, while Dr. B. states that the military records did not indicate a return to normal levels, the Board notes that SGOT testing in October 1969 was in fact within normal limits. Moreover, while infectious mononucleosis was noted in the September 1971 separation examination report, no mention is made of liver disease. Furthermore, while infectious mononucleosis was diagnosed in January 1969, there is no reliable evidence of current residuals of infectious mononucleosis, to include liver disease and/or the necessity of a liver transplant. The March 2003 VA examiner specifically stated that it was not likely that the appellant's liver disease had any relationship to his bout with infectious mononucleosis during service. To the extent that Dr. B. asserted that SGOT levels in service represented liver disease or hepatitis, the Board again notes that the March 2003 VA examiner specifically stated that while 90 percent of patients with mononucleosis had elevation of hepatic transaminases, mononucleosis was not an etiology for cirrhosis of the liver. As specifically stated by both Dr. B. and the March 2003 VA examiner, cryptogenic cirrhosis refers to cirrhosis of unknown or indeterminate etiology. The appellant's assertions that he had liver disease during service are unsupported and not competent. While service medical records show the appellant had some elevated serum glutamic oxaloacetic transaminase (SGOT) levels, liver disease was noit diagnosed in service. Although not controlling, the decision of the in-service examiner to not enter a liver disease diagnosis is a fact to be considered when balancing other evidence. On discharge examination in September 1971, the abdomen and viscera were clinically normal, and the veteran certified that he was in good health. The examiner noted that infectious mononucleosis was diagnosed in 1969. He was found the veteran qualified for separation. The Board notes that cirrhosis of the liver is listed as a disease subject to service connection pursuant to 38 U.S.C.A. §§ 1101, 1112, 1113 and 38 C.F.R. §§ 3.307, 3.309 (presumptions for certain chronic diseases). The competent evidence shows that liver disease was not manifest during service or within one year of separation from service. Private treatment records first reflect a diagnosis of cirrhosis of the liver in October 1996. The veteran underwent a liver transplant in June 1997 with a diagnosis of cryptogenic cirrhosis. In regard to the appellant's assertion that his liver disease is related to exposure to Agent Orange exposure during service in Vietnam, the Board notes it is clear from the appellant's DD Form 214 that he served in Vietnam, and is presumed to have been exposed to Agent Orange. The appellant's liver disease, however, is not a disease which is presumptive of service-connection by reason of having a positive association with exposure to an herbicide agent. To the extent that the appellant's private physician, Dr. D has related the appellant's liver disease to exposure to Agent Orange, the Board notes that that the Secretary of VA has determined that there is no positive association between exposure to herbicides and any other condition for which the Secretary has not specifically determined that a presumption of service connection is warranted. See Notice, 61 Fed. Reg. 57586-57589 (1996); 64 Fed. Reg. 59232-59243 (1999); 67 Fed. Reg. 42600-42608 (2002). Although not determinative, it is a fact to be considered. With respect to direct service connection, as noted, service medical records are negative for a diagnosis of liver disease. At separation, the abdomen and viscera were normal. Liver disease was not diagnosed until October 1996, many years after service. While Dr. C. has related the appellant's liver disease to exposure to Agent Orange, his April 1998 opinion was equivocal, stating that Agent Orange may have played a role in the appellant's development of liver disease. His September 2002 opinion, while less ambiguous, is lacking a foundation and of diminished probative value. The Board has been presented with positive and negative evidence. The opinions of Dr. C. are conclusory and nothing more than a statement of opinion. A mere statement of opinion, without more, does not provide an opportunity to explore the basis of the opinion. See Murphy v. Derwinski, 1 Vet. App. 78, 81-82 (1990). In regard to the opinions of Dr. B. and the VA examiner, each opinion is reasoned. However, the opinion of the VA examiner is more convincing and more consistent with the record. The Board again observes that no diagnosis of liver disease was made in service, or within an appropriate presumptive period following service. Furthermore, the treating providers and VA examiner have entered a diagnosis of "cryptogenic cirrhosis," which means that no etiology was found. On the other hand, Dr. B.' s statement that the veteran developed liver disease in service is not supported by the record. As discussed, while the service medical records show elevated liver enzymes in 1969, they do not reflect a diagnosis of liver disease. Dr. B.' s suggestion that the veteran's exposure to some hepatic cell damaging infection or toxin, leading to eventual liver disease, is unsupported by the record. Moreover, he also indicates that liver damage was incurred during service. However, the service medical records do not reflect such findings, and the VA examination conducted directly after the veteran's separation is also negative in this regard. The Board again notes that we do not require an in-service diagnosis. However, the absence of manifestations to support a diagnose and the decision of the examiners that there were normal findings at that time are facts that are considered when assigning probative weight to other evidence. The Board finds the March 2003 VA opinion to be unequivocal and more probative. That examiner specifically stated that it was not likely that the appellant's liver disease was due to Agent Orange exposure, noting no scientific data showing any link between liver disease and exposure to Agent Orange. He based his opinions on a complete review of the veteran's records and a consultation with a gastroenterologist. In regard to service connection for residuals of infectious mononucleosis, as noted, the evidence establishes that liver disease is not a related to infectious mononucleosis. No residuals of in-service infectious mononucleosis are shown. The determination of this matter requires competent evidence. The appellant is competent to report his symptoms. His opinion in regard to etiology, however, is not competent evidence, as he is a layperson. Espiritu v. Derwinski, 2 Vet. App. 492, 495 (1992). In summary, the most probative evidence establishes that liver disease did not have an onset in service, is not a residual of infectious mononucleosis, and is not a result of exposure to Agent Orange during service. No residuals of infectious mononucleosis are shown. The probative evidence establishes that the etiology of the appellant's cirrhosis of the liver is unknown. The preponderance of the evidence is against the claim and there is no doubt to be resolved. Consequently, the benefit sought on appeal is denied. ORDER Service connection for infectious mononucleosis residuals is denied. Service connection for liver disease is denied. ____________________________________________ H. N. SCHWARTZ Veterans Law Judge, Board of Veterans' Appeals Department of Veterans Affairs