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Multiple Sclerosis Centers of Excellence


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Diagnosing Multiple Sclerosis

The diagnosis of MS can only be made after an extensive evaluation and is not based on one specific physical finding, laboratory test or symptom. The diagnosis of MS is often difficult and may take time. The symptoms of MS can come and go, and symptoms are not the same for every person. A Health Care Provider will take a clinical history and perform a physical examination. Although many of the symptoms cannot be seen on examination, there are specific guidelines that have been developed to help a Health Care Provider (usually a Neurologist) make the diagnosis of MS. Additional testing may be necessary, including imaging (an MRI) of the head and neck, blood tests, spinal fluid analysis, and visual tests. The VA is committed to providing our Veterans the specialized testing needed to establish an accurate diagnosis of MS.


Diagnosing MS Using the McDonald Criteria
Describes the 2010 Revised Criteria with Tip Sheet

Determination of MS Subtypes
Describes the most widely used MS subtype descriptors which are FDA indicated for DMTs and the proposed MS subtypes.

Multiple Sclerosis: A Therapeutic Overview
Mark H. J. Litzinger, BSc, BSc Pharm, RPh-University of Hawaii at Hilo
Monica Litzinger, BSc, BSc Pharm, RPh-Community Pharmacist, Hilo, Hawaii

What is Transverse Myelitis?
National Institute of Neurological Disorders and Stroke
National Institutes of Health--Bethesda, Maryland

MS for Primary Care Providers a PowerPoint Slide Presentation
Ruth Whitham, MD-VA MS Centers of Excellence
Portland, Oregon, VA Medical Center

Diagnosing and Managing MS Relapses
Discusses relapse symptoms and treatment approaches

MS Self-report Questionnaires: Fatigue and Sexual Function
Marsha L Tarver, PhD, MA
VA MS Centers of Excellence--Seattle

Kurtzke Expanded Disability Status Scale (EDSS)
Marsha L Tarver, PhD, MA
VA MS Centers of Excellence--Seattle

The Evolution of the Multiple Sclerosis Lesion