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Research Advisory Committee on Gulf War Veterans' Illnesses


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Research Update - August 2006

The following journal articles were distributed for review in August 2006.  You can access the article's abstract by copying the paper title and pasting it into the search bar of the PubMed website, linked here. 

Research Relevant to Gulf War Service and Exposures
1. Symptoms, ill-health and quality of life in a support group of Porton Down veterans.  (Allender S, et al.  Occup Med (Lond).  Jul 17, 2006; [Epub ahead of print])
2. Cholinergic overstimulation supports conditioned-facilitated startle but no conditioned hyperalgesia.  (Beck KD, et al.  Pharmacol Biochem Behav.  Jul 14, 2006; [Epub ahead of print])
3. Mustard lung secrets: Long term clinicopathological study following mustard gas exposure.  (Beheshti J, et al.  Pathol Res Pract.  Aug 1, 2006; [Epub ahead of print])
4. The evolution of depleted uranium as an environmental risk factor: lessons from other metals.  (Briner WE.  Int J Environ Res Public Health. Jun 2006; 3(2): 129-135)
5. Expression profiling of human epidermal keratinocyte response following 1-minute JP-8 exposure.  (Chou CC, et al.  Cutan Ocul Toxicol.  2006; 25(2): 141-153)
6. Short-term effects of depleted uranium on immune status in rat intestine.  (Dublineau I, et al.  J Toxicol Environ Health A.  Sep 2006; 69(17): 1613-1628)
7. Spouses of Persian Gulf War I veterans: medical evaluation of a US cohort.  (Eisen SA, et al.  Mil Med.  Jul 2006; 171(7): 613-618)
8. Pain among veterans of Operations Enduring Freedom and Iraqi Freedom.  (Gironda RJ, et al.  Pain Med.  Jul 2006; 7(4): 339-343)
9. What was different about exposures reported by male Australian Gulf War veterans for the 1991 Persian Gulf War, compared with exposures reported for other deployments?  (Glass DC , et al.  Mil Med.  Jul 2006; 171(7): 632-638)
10. Anxiety, depression, and posttraumatic stress in Iranian survivors of chemical warfare.  (Hashemian F, et al.  JAMA.  Aug 2, 2006; 296(5): 560-566)
11. Neuropsychological changes following military service in Iraq: case proven, but what is the significance?  (Hotopf M, Wessely S.  JAMA.  Aug 2, 2006; 296(5): 574-575)
12. Mental health after deployment to Iraq or Afghanistan.  (Larson GE, et al.  JAMA.  Aug 2, 2006; 296(5): 514-515; author reply 516)
13. The war-related illness and injury study centers: a resource for deployment-related health concerns.  (Lincoln AE, et al.  Mil Med.  Jul 2006; 171(7): 577-585)
14. Familial aggregation of fainting in a case-control study of neurally-mediated hypotension patients who present with unexplained chronic fatigue.  (Lucas KE, et al.  Europace.  Aug 18, 2006; [Epub ahead of print])
15. Distribution and genotoxic effects after successive exposure to different uranium oxide particles inhaled by rats.  (Monleau M, et al.  Inhal Toxicol.  Oct 2006; 18(11): 885-894)
16. Is the increased reporting of symptomatic ill health in Gulf War veterans related to how one asks the question?  (Murphy D, et al.  J Psychosom Res.  Aug 2006; 61(2): 181-186)
17. A search for cellular and molecular mechanisms involved in depleted uranium (DU) toxicity.  (Pourahmad J, et al.  Environ Toxicol.  Jul 13, 2006; 21(4): 349-354 [Epub ahead of print])
18. Circadian rhythms of heart rate and locomotion after treatment with low-dose acetylcholinesterase inhibitors.  (Scremin OU, et al.  J Appl Toxicol.  Jul 20, 2006; [Epub ahead of print])
19. Analysis of anthrax and plague biowarfare vaccine interactions with human monocyte-derived dendritic cells.  (Skowera A, et al.  J Immunol.  Dec 1, 2005; 175(11): 7235-7243)
20. Depleted uranium and cancer in Danish Balkan veterans deployed 1992-2001.  (Storm HH, et al.  Eur J Cancer.  Jul 18, 2006; [Epub ahead of print])
21. Comparison of Acinetobacter baumanni isolates from the United Kingdom and the United States that were associated with repatriated casualties of the Iraq conflict.  (Turton JF, et al.  J Clin Microbiol.  Jul 2006; 44(7): 2630-2634)
22. Neuropsychological outcomes of army personnel following deployment to the Iraq war.  (Vasterling JJ, et al.  JAMA.  Aug 2, 2006; 296(5): 519-529)
23. New-onset rheumatoid arthritis after anthrax vaccination.  (Vasudev M, Zacharisen MC.  Ann Allergy Asthma Immunol.  Jul 2006; 97(1): 110-112.
24. Self-reported reproductive outcomes among male and female 1991 Gulf War era US military veterans.  (Wells TS, et al.  Matern Child Health J.  Jul 11, 2006; [Epub ahead of print])

25. Mental distress among younger veterans before, during, and after the invasion of Iraq.  (West AN, Weeks WB.  Psychiatr Serv.  Feb 2006; 57(2): 244-248)

26. Multiple vaccine and pyridostigmine interactions: Effects of EEG and sleep in the common marmoset.  (Williams KE, et al.  Pharmacol Biochem Behav.  Jul 5, 2006; [Epub ahead of print])

27. The inflammatory NADPH oxidase enzyme modulates motor neuron degeneration in amyotrophic lateral sclerosis mice.  (Wu DC , et al.  Proc Natl Acad Sci U S A.  Jul 28, 2006; [Epub ahead of print])

Research on Evaluation/Treatment of Chronic Multisymptom Illnesses
1. Cognitive behavioral therapy for fibromyalgia.  (Bennett R, Nelson D.  Nat Clin Pract Rheumatol.  Aug 2006; 2(8): 416-424)
2. Biology and therapy of fibromyalgia. Genetic aspects of fibromyalgia syndrome.  (Buskila D, Sarzi-Puttini P.  Arthritis Res Ther.  Jul 28, 2006; 8(5): 218 [Epub ahead of print])
3. A new application of sound resonance technology therapy for the treatment of fibromyalgia: A retrospective analysis.  (Cogan J, et al.  Complement Ther Clin Pract.  Aug 2006; 12(3): 206-212)
4. Therapy insight: fibromyalgia – a different type of pain needing a different type of treatment.  (Dadabhoy D, Clauw DJ.  Nat Clin Pract Rheumatol.  Jul 2006; 2(7): 364-372)
5. Long-term follow up of a physical therapy programme for patients with fibromyalgia syndrome.  (Havermark AM, Langius-Eklof A.  Scand J Caring Sci.  Sep 2006; 20(3): 315-322)

6. An open-label study of quetiapine in the treatment of fibromyalgia.  (Hidalgo J, et al.  Prog Neuropsychopharmacol Biol Psychiatry.  Aug 2, 2006; [Epub ahead of print])
7. Urinary cortisol and cortisol metabolite excretion in chronic fatigue syndrome.  (Jerjes WK, et al.  Psychosom Med.  Jul-Aug 2006; 68(4): 578-582)
8. Chronic widespread pain and its comorbidities: a population-based study.  (Kato K, et al.  Arch Intern Med.  Aug 14, 2006; 166(15): 1649-1654)
9. Current research priorities in chronic fatigue syndrome / myalgic encephalomyelitis (CFS/ME): disease mechanisms, a diagnostic test and specific treatments.  (Kerr JR, et al.  J Clin Pathol.  Aug 25, 2006; [Epub ahead of print])
10. Emerging pharmacological therapies for fibromyalgia.  (Lawson K.  Curr Opin Investig Drugs.  Jul 2006; 7(7): 631-636)
11. Cerebrospinal fluid corticotrophin-releasing factor concentration is associated with pain but no fatigue symptoms in patients with fibromyalgia.  (McLean SA, et al.  Neuropsychopharmacology.  Aug 23, 2006; [Epub ahead of print])
12. Chronic musculoskeletal pain in patients with the chronic fatigue syndrome: A systematic review.  (Meeus M, et al.  Eur J Pain.  Jul 12, 2006; [Epub ahead of print])
13. Factors that affect the number of tender points in fibromyalgia and chronic widespread pain patients who did not meet the ACR 1990 Criteria for Fibromyalgia: Are tender points a reflection of neuropathic pain?  (Pamuk ON , et al.  Semin Arthritis Rheum.  Jul 13, 2006; [Epub ahead of print])
14. Is milnacipran effective in treating pain in patients with fibromyalgia?  (Simon LS. Nat Clin Pract Rheumatol.  Mar 2006; 2(3): 126-127)
15. Mortality in a cohort of chronically fatigued patients.  (Smith WR, et al.  Psychol Med.  Sep 2006; 36(9): 1301-1306)
16. Mechanisms of disease: pain in fibromyalgia syndrome.  (Staud R, Rodrigeuz ME.  Nat Clin Pract Rheumatol.  Feb 2006; 2(2): 90-98)
17. Psychological pain treatment in fibromyalgia syndrome: efficacy of operant-behavioral and cognitive-behavioral treatments (ISRCTN83953414).  (Thieme K, et al.  Arthritis Res Ther.  Jul 19, 2006; 8(4): R121 [Epub ahead of print])
18. Reduced levels of anti-inflammatory cytokines in patients with chronic widespread pain.  (Uceyler N, et al.  Arthritis Rheum.  Jul 26, 2006; 54(8): 2656-2664 [Epub ahead of print])
19. Azithromycin in chronic fatigue syndrome (CFS), an analysis of clinical data.  (Vermeulen RC, Scholte HR.  J Transl Med.  Aug 15, 2006; 4(1): 34 [Epub ahead of print])
20. Functionally oriented rehabilitation program for patients with fibromyalgia: preliminary results.  (Wennemer HK, et al.  Am J Phys Med Rehabil.  Aug 2006; 85(8): 659-666)

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