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VA » Health Care » Multiple Sclerosis Centers of Excellence » Teriflunomide (Aubagio)

Multiple Sclerosis Centers of Excellence

Teriflunomide (Aubagio)

Teriflunomide (Aubagio) is a once daily, oral medication for the treatment of relapsing forms of MS. Teriflunomide, an immunomodulatory agent with anti-inflammatory properties, inhibits dihydroorotate dehydrogenase, a mitochondrial enzyme involved in de novo pyrimidine synthesis. It may produce a reduction in the number of activated lymphocytes in the CNS. Teriflunomide has restricted distribution under the REMS program as is limited to registered prescribers and pharmacies.

Additional Information

National MS Society Aubagio
VA Teriflunomide (Aubagio) Criteria for Use (VA access only)
VA Teriflunomide (Aubagio) Drug Monograph (VA access only)

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