Geriatric Research Education and Clinical Center (GRECC)

• Mechanisms of recovery and novel treatments for neurodegenerative disease, stroke and vascular dementia, and TBI chronic traumatic encephalopathy
• Novel rehabilitations strategies for stroke, aphasia, frailty and cardiac disorder
• Developing novel clinical care systems for pain and dementia
• Polypharmacy and medication errors in the elderly

• Molecular and cellular mechanisms underlying aging related cognitive and sensorimotor impairment due to cerebral ischemia and traumatic brain injury
• Telemedicine, medication safety, polypharmacy and patient safety in the post-acute and long term care setting
• Neural and cognitive mechanisms underlying language and communicative impairments and their treatment in post-stroke aphasia
• Optimizing evaluation and management of chronic low back pain and lumbar spinal stenosis in older adults
• Cellular and molecular mechanisms underlying neurodegeneration in progressive supranuclear palsy and related tauopathies
• Enhancing functional capacity in older adults with cardiovascular disease, in respect to both process of care and underlying subcellular mechanisms
• Molecular mechanisms that drive aging and age-associated pathologies
• Synaptic and neurotransmitter changes associated with age-related neurodegenerative disease; cellular and molecular processes underlying aging and Alzheimer’s disease
• Recovery of motor function after stroke

• Interactive interprofessional education activities during which students teach each other
• Training of primary care-based practitioners in evidence-based interdisciplinary chronic pain management
• Advanced training in geriatrics scholarship following completion of clinical training

• Improved access of rural Veterans with cognitive decline to interdisciplinary telehealth team
• Collaboration regarding telehealth care to rural Veterans w/other GRECC clinical teams throughout the nation in the Virtual Geriatrics group (previously GRECC Connect)
• Implemented e-consults to reconcile medications and deprescribe inappropriate medications in older Veterans
• Ongoing intensive therapy program to improve aphasia (Program of Intensive Residential Aphasia Treatment and Education - PIRATE) and successful implementation to other sites
• Virtual caregiver support program for caregivers of Veterans with dementia
• Innovative cardiac rehab program that manages cardiovascular disease in older adults and addresses the context of multimorbidity, frailty, cognitive impairment, disability and polypharmacy

Robot-Assisted Arm Training in Chronic Stroke: Addition of Transition-to-Task Practice Neurorehabil Neural Repair https://pubmed.ncbi.nlm.nih.gov/31328671/

Aging Back Clinics-a Geriatric Syndrome Approach to Treating Chronic Low Back Pain in Older Adults: Results of a Preliminary Randomized Controlled Trial Pain Med https://pubmed.ncbi.nlm.nih.gov/31503275/

Central Nervous System Medication Burden and Risk of Recurrent Serious Falls and Hip Fractures in Veterans Affairs Nursing Home Residents J Am Geriatr Soc https://pubmed.ncbi.nlm.nih.gov/30306541/

Frailty Among Older Adults With Acute Myocardial Infarction and Outcomes From Percutaneous Coronary Interventions J Am Heart Assoc https://pubmed.ncbi.nlm.nih.gov/31475601/

Role of UCHL1 in axonal injury and functional recovery after cerebral ischemia Proceedings of the National Academy of Sciences https://www.researchgate.net/publication/331095767_Role_of_UCHL1_
in_axonal_injury_and_functional_recovery_after_cerebral_ischemia