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Minneapolis VA Health Care System Research Service

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Investigator Profile

Christine Wendt

Christine Wendt, MD

Section Chief, Pulmonary, Allergy, Critical Care and Sleep, Minneapolis VA
Professor of Medicine, University of Minnesota
BS, MD University of Minnesota
Contact Information
Research Interests
I am a Professor of Medicine and Section Chief of Pulmonary, Allergy, Critical Care, and Sleep (PACCS) at the Minneapolis VAMC. Our section is a national leader in COPD research. My research has focused on both clinical and translational research in COPD and associated contributors including tobacco, HIV, air pollution and COPD as a causal pathway to lung cancer. For my translational research using a multi-omic approach including genomics, transcriptomics, proteomics, metabolomics, computational and systems biology I have identified biomarkers and causal pathways in COPD leading to lung cancer and HIV-associated COPD. I have participated on five large NIH COPD trials, including the NIH COPD Clinical Research Network and the VA Lung Precision Oncology Program. I have also directed a pilot RCT to explore the role of the microbiome in COPD exacerbations and symptoms. My interest in air pollution and chronic lung disease dates to my participation as a delegate for the University of Minnesota and Chinese Academy of Science to address the health effects of air pollution in China. I have extended this area of research to include epidemiology and respiratory effects of deployment-related air pollution exposure, including burn pit exposure. My research has focused on biomarkers of disease using high-throughput mass spectrometry, specifically focusing on chronic obstructive lung diseases. I have a long-standing interest in clinical and translational research in COPD.
Full bibliography on PubMed
VA Research Topics
Respiration & Pulmonary Disease;
MeSH Key Words
Proteomics; Metabolomics; Biomarkers; Pulmonary Disease, Chronic Obstructive; Lung Neoplasms; Air Pollution; Lung Diseases; Microbiota; HIV Infections
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ORCID | Google Scholar
University of Minnesota profile