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Research Health Scientist, Minneapolis VA Chair, Institutional Animal Care and Use Committee, Minneapolis VA Adjunct Assistant Professor, Department of Laboratory Medicine and Pathology, University of Minnesota
. This work emphasizes defining the roles of these kinases in different cancer types, and the mechanisms by which these molecules contribute to malignant cell signaling. As a member of the Minneapolis VA Oncology Research Group, I have studied cancers of the breast, prostate, head and neck, and skin. The overall goal of these investigations is to understand and exploit cancer cell dependencies on
function to improve therapeutic strategies in these malignancies. As a member of the Environmental Exposure Research Group, I am also working on investigating the pathobiology of Chronic Multi-symptom Illness (CMI).
is a major health concern for Veterans of the Gulf War and those who served in Iraq and Afghanistan. These studies involve measurement of biomarkers in the blood of Veterans as well as in the tissues of rodents exposed to whole body inhalation models of military burn pits. The goals are to define biomarkers of response and understand biological dysregulation following exposures in order to determine possible methods of intervention.
RNA Polymerase II; Phosphorylation; Casein Kinase II; Cyclin-Dependent Kinases; Signal Transduction; Head and Neck Neoplasms; Melanoma; Prostatic Neoplasms; Breast Neoplasms; RNA Splicing; Mitochondria; Cell Death