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The major focus of Dr. Urošević's program of research is investigating neural and behavioral abnormalities that contribute to the etiology and prediction of prospective illness course in bipolar disorders (BD) across the lifespan. In her studies of BD, she has used a variety of methodologies (self-report, behavioral tasks, electroencephalography (EEG), functional magnetic resonance imaging (fMRI)) to examine the effects of behavioral approach system (BAS) dysregulation on prospective bipolar symptoms/episodes in adults with BD using longitudinal study designs with prospective interview-based clinical assessments. As part of her NIMH K01 Career Development Award, Dr. Urošević investigated developmental changes in reward/BAS and cognitive control system’s neurobehavioral functioning in a large sample of adolescents with BD and typically developing adolescents. More recently, Dr. Urošević expanded her research into areas of aging and mHealth. For example, she examined steeper aging-related declines in these reward and cognitive control dimensions among older Veterans with BD compared to older Veterans without major mental disorders using neuropsychological measures. Dr. Urošević is also the PI for the VA RR&D SPiRE project (I21 RX003298) assessing prospective changes in social engagement, suicidality, and bipolar symptoms using digital phenotyping methods.